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Project Title |
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DNA
associates with histon proteins in
higher eukaryotic cells, compactifying million-fold. The resulting
chromatin fibers are very dynamic, regulating gene
transcription.
Using all-atom and coarse-grained molecular dynamics simulations, we
are developing new insights into the chromatin fiber structure
and
stability. Learn
more... |
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Alex
Savelyev |
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Using
tools from diverse areas of
physics and bioinformatics we are building nonequilibrium statistical
mechanics of signal transduction networks. In particular, we are
interested in spatio-temporal regulation of eukaryotic cell motility. Learn
more... |
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Natsuki Tanaka, Pavel Zhuravlev |
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We
are developing an integrated system of multi-scale computational
techniques, from very coarse-grained to all-atom models, to describe
the native dynamics of various enzymes and signaling proteins. In a
related project, we are working on new free energy computational
methods for proteins. Learn
more... |
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Chris
Materese, Sean Walder, Sangwook Wu, Pavel Zhuravlev |
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